Methanol → 5-[(3-Chlorophenyl)methyl]4-{2-[(1,1-dimethylethyl)dimethylsilyl]oxyethoxy}thiophene-3-carboxylic acid
Reaction equation
[CH3:31][OH:32].[Cl:1][c:2]1[cH:3][c:4]([CH2:8][c:9]2[c:10]([O:18][CH2:19][CH2:20][O:21][Si:22]([CH3:23])([CH3:24])[C:25]([CH3:26])([CH3:27])[CH3:28])[c:11]([C:14](=[O:15])[O:16][CH3:17])[cH:12][s:13]2)[cH:5][cH:6][cH:7]1.[Li+:29].[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1.[OH-:30]>>[Cl:1][c:2]1[cH:3][c:4]([CH2:8][c:9]2[c:10]([O:18][CH2:19][CH2:20][O:21][Si:22]([CH3:23])([CH3:24])[C:25]([CH3:26])([CH3:27])[CH3:28])[c:11]([C:14](=[O:15])[OH:16])[cH:12][s:13]2)[cH:5][cH:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-3562f5b5465e4bdc840fc81b967edc2c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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