反应详情

The product from Step (a) (2 g) was dissolved in dioxane (100 ml) and 6N HCl (100 ml) added. After 18 hours at room temperature the solvent was evaporated and the resultant solid basified with NaOH (2N) to pH 11. The aqueous was extracted with ethyl acetate, the organic phase separated, dried with MgSO4 and evaporated to leave the sub-title compound as an oil (1.1 g).

1. customAfter 18 hours at room temperature the solvent was evaporated
2. extractionThe aqueous was extracted with ethyl acetate
3. customthe organic phase separated
4. dry with materialdried with MgSO4
5. customevaporated