4-Methoxyphenol → HCID 23516352, compound

HRID 970246Notes

Reaction equation

HRID 970246 reaction equation
[C:1]([O:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][O:12][C:13]1[CH:34]=[CH:33][C:16]([C:17]([O:19][C:20]2[CH:32]=[CH:31][C:23]([C:24]([O:26]COCC)=[O:25])=[CH:22][CH:21]=2)=[O:18])=[CH:15][CH:14]=1)(=[O:4])[CH:2]=[CH2:3].C1(C)C=CC(S([O-])(=O)=O)=CC=1.[NH+]1C=CC=CC=1.COC1C=CC(O)=CC=1>C(O)C>[C:1]([O:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][O:12][C:13]1[CH:34]=[CH:33][C:16]([C:17]([O:19][C:20]2[CH:32]=[CH:31][C:23]([C:24]([OH:26])=[O:25])=[CH:22][CH:21]=2)=[O:18])=[CH:15][CH:14]=1)(=[O:4])[CH:2]=[CH2:3]

Participants

5

Reactant 3

HCID 90154-MethoxyphenolHCID 466102Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1)HCID 58935103HCID 58935103, compound

Product 1

HCID 23516352HCID 23516352, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
60 °C

Procedure

98.5g (0.2 mole) of ethoxymethyl 4-(4-(6-acryloyloxyhexyloxy)-benzoyloxy)-benzoate (12) were dissolved in 400 ml of ethanol and 5 g (0.02 mole) of pyridinium 4-toluenesulfonate and 20 mg of 4-methoxyphenol were added. The mixture was heated at 60° C. for 15 h. After cooling down to room temperature the product crystallized. It was collected, washed with 300 ml of ethanol, and dried in the desiccator after which 55.3 g of a white powder (67%) were obtained.

Workup

  1. temperatureAfter cooling down to room temperature the product
  2. customcrystallized
  3. customIt was collected
  4. washwashed with 300 ml of ethanol
  5. dry with materialdried in the desiccator after which 55.3 g of a white powder (67%)
  6. customwere obtained

Sources & evidence

ORD record
ord-9b561dcb938449ffad2e1a2508075605
Source dataset
uspto-grants-2007_12
Patent number
US07311948B2

Reaction notes

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