Dimethylformamide → 3-(2-Chloropyridin-4-yloxy)-4-fluoro-N-(2-fluoro-5-methylphenyl)benzamide

HRID 97092Notes

Reaction equation

HRID 97092 reaction equation
[CH3:52][N:53]1[CH2:54][CH2:55][O:56][CH2:57][CH2:58]1.[CH3:59][N:60]([CH3:61])[CH:62]=[O:63].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([O:8][c:9]2[cH:10][c:11]([C:12](=[O:13])[OH:14])[cH:15][cH:16][c:17]2[F:18])[cH:7]1.[F:19][c:20]1[c:21]([NH2:22])[cH:23][c:24]([CH3:27])[cH:25][cH:26]1.[F:28][P-:29]([F:30])([F:31])([F:32])([F:33])[F:34].[n:35]1([O:36][C:37]([N:38]([CH3:39])[CH3:40])=[N+:41]([CH3:42])[CH3:43])[c:44]2[n:45][cH:46][cH:47][cH:48][c:49]2[n:50][n:51]1>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([O:8][c:9]2[cH:10][c:11]([C:12](=[O:14])[NH:22][c:21]3[c:20]([F:19])[cH:26][cH:25][c:24]([CH3:27])[cH:23]3)[cH:15][cH:16][c:17]2[F:18])[cH:7]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 79724-MethylmorpholineHCID 9886HexafluorophosphateHCID 2629702-Fluoro-5-methylanilineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 581677923-(2-Chloropyridin-4-yloxy)-4-fluorobenzoic acid

Product 1

HCID 866515583-(2-Chloropyridin-4-yloxy)-4-fluoro-N-(2-fluoro-5-methylphenyl)benzamide

Sources & evidence

ORD record
ord-e3ebc821d39e4325b9c8978522ca2bcc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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