Thiophenol → 5-Phenylsulfanyl-indan-1-one

HRID 971279Notes

Reaction equation

HRID 971279 reaction equation
F[C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[C:7](=[O:11])[CH2:6][CH2:5]2.[C:12]1([SH:18])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.C(=O)([O-])[O-].[K+].[K+]>>[C:12]1([S:18][C:2]2[CH:3]=[C:4]3[C:8](=[CH:9][CH:10]=2)[C:7](=[O:11])[CH2:6][CH2:5]3)[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

4

Reactant 3

HCID 7969ThiophenolHCID 11430Potassium CarbonateHCID 1365375-Fluoro-1-indanone

Product 1

HCID 125519925-Phenylsulfanyl-indan-1-one

Procedure

5-Fluoro-1-indanone from Aldrich Sigma Chemical Co. (Cat No. 18,566-3) was treated with benzenethiol in the presence of potassium carbonate using the procedure of step 4 of Example 1 to afford 5-phenylsulfanyl-indan-1-one. MS: 241 (M+H)+.

Sources & evidence

ORD record
ord-b93039970709431e91d346acbf9702d0
Source dataset
uspto-grants-2007_12
Patent number
US07312359B2

Reaction notes

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