反应详情

14.1 g of Z-Gln-Asn-Phe-OCH3 are hydrogenated at 45° C. in 800 ml of methanol with the addition of 8.5 ml of 3N-hydrogen chloride in dioxan and 2.4 g of 10% palladium carbon. When the hydrogen uptake ceases, the batch is filtered and evaporated. The residue is processed without purification.

1. filtrationWhen the hydrogen uptake ceases, the batch is filtered
2. customevaporated
3. customThe residue is processed without purification