2-Mercaptoethanol → HCID 22624790, compound

HRID 972086Notes

Reaction equation

HRID 972086 reaction equation
[CH3:1][C:2]1[C:7]([CH2:8]Cl)=[C:6]([CH3:10])[CH:5]=[C:4]([C:11]([CH3:14])([CH3:13])[CH3:12])[C:3]=1[OH:15].[SH:16][CH2:17][CH2:18][OH:19].C(=O)([O-])[O-].[K+].[K+].[I-].[K+]>C(C(C)=O)C(C)C>[CH3:1][C:2]1[C:7]([CH2:8][S:16][CH2:17][CH2:18][OH:19])=[C:6]([CH3:10])[CH:5]=[C:4]([C:11]([CH3:14])([CH3:13])[CH3:12])[C:3]=1[OH:15]

Participants

6

Reactant 4

HCID 15672-MercaptoethanolHCID 4875Potassium IodideHCID 11430Potassium CarbonateHCID 901316-tert-Butyl-3-(chloromethyl)-2,4-dimethylphenol

Product 1

HCID 22624790HCID 22624790, compound

Reagents, catalysts & solvents 1

HCID 7909Methyl Isobutyl KetoneSolvent

Procedure

This material was prepared according to the procedure of Example III using 2,4-dimethyl-3-chloromethyl-6-t-butylphenol (160.8 g, 0.71 m), 2-mercaptoethanol (52.5 g, 0.71 m), potassium carbonate (110.4 g, 0.8 m), potassium iodide (5.0 g), and methyl isobutyl ketone (500 ml). Work-up afforded a dark colored oil. This material can be distilled under a very good vacuum. The nmr spectrum was consistent with the desired structure.

Workup

  1. customThis material was prepared
  2. customWork-up afforded a dark colored oil
  3. distillationThis material can be distilled under a very good vacuum

Sources & evidence

ORD record
ord-7cc22b8833d54762b6223383f5c721de
Source dataset
uspto-grants-1979_07
Patent number
US04163008

Reaction notes

Loading…