Triethylamine → HCID 20396662, compound

HRID 972132Notes

Reaction equation

HRID 972132 reaction equation
[CH3:1][O:2][CH:3]([O:13][CH3:14])[CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([OH:12])=[CH:8][CH:7]=1.[CH2:15]([N:18]([CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[C:19](Cl)=[O:20])[CH:16]=[CH2:17].C(N(CC)CC)C>C1(C)C(C)=CC=CC=1>[CH2:15]([N:18]([CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[C:19](=[O:20])[O:12][C:9]1[CH:10]=[CH:11][C:6]([O:5][CH2:4][CH:3]([O:2][CH3:1])[O:13][CH3:14])=[CH:7][CH:8]=1)[CH:16]=[CH2:17]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 20396656HCID 20396656, compoundHCID 21822430HCID 21822430, compound

Product 1

HCID 20396662HCID 20396662, compound

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

4-(2,2-Dimethoxyethoxy)phenol (0.05 mole), N-allyl-N-benzylcarbamoyl chloride (0.08 mole), triethylamine (0.05 mole) and xylene (50 ml) are charged into a glass reaction flask equipped with a mechanical stirrer, thermometer and reflux condenser. The mixture is stirred and heated at reflux for a period of about 12 hours. After this time the reaction mixture is cooled to room temperature and is filtered. The filtrate is then washed with water and dried over anhydrous magnesium sulfate. The dried solution is then filtered and stripped of solvent and unreacted starting materials to yield the desired product O-[4-(2,2-dimethoxyethoxy)phenyl] N-allyl-N-benzylcarbamate as the residue.

Workup

  1. customequipped with a mechanical stirrer
  2. temperaturethermometer and reflux condenser
  3. temperatureheated
  4. temperatureat reflux for a period of about 12 hours
  5. filtrationis filtered
  6. washThe filtrate is then washed with water
  7. dry with materialdried over anhydrous magnesium sulfate
  8. filtrationThe dried solution is then filtered

Sources & evidence

ORD record
ord-7d2d49d39e014b5c82f72a55f4407e0b
Source dataset
uspto-grants-1979_07
Patent number
US04163112

Reaction notes

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