反应详情

温度

50 °C

A solution of 32.5 g of 2-(3-dimethylaminopropoxy)benzaldehyde and 18.9 g of phenethylamine in 150 ml of toluene is heated at reflux for 1 hour. After 30 minutes, one mole equivalent of water is collected in a Dean-Stark trap. After cooling to approximately 50° C., the solvent is removed using a rotary evaporator and the oily residue is distilled to give 36.2 g of the title compound, boiling point 165°-167° C. at 0.05 mm of Hg.

1. temperatureat reflux for 1 hour
2. customone mole equivalent of water is collected in a Dean-Stark trap
3. customthe solvent is removed
4. customa rotary evaporator
5. distillationthe oily residue is distilled