3-Methoxyaniline → N-(3-Methoxyphenyl)tricyclo[3.3.1.13,7]decane-1-carboxamide

HRID 972647Notes

Reaction equation

HRID 972647 reaction equation
[C:1]12([C:11](Cl)=[O:12])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[CH3:14][O:15][C:16]1[CH:21]=[CH:20][CH:19]=[C:18]([NH2:22])[CH:17]=1>C(N(CC)CC)C>[CH3:14][O:15][C:16]1[CH:17]=[C:18]([NH:22][C:11]([C:1]23[CH2:10][CH:5]4[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]4)[CH2:2]2)[CH2:8]3)=[O:12])[CH:19]=[CH:20][CH:21]=1

Participants

4

Reactant 2

HCID 108243-MethoxyanilineHCID 989151-Adamantanecarbonyl chloride

Product 1

HCID 5151025N-(3-Methoxyphenyl)tricyclo[3.3.1.13,7]decane-1-carboxamide

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

Subject 6.5 g. of adamantane carboxylic acid chloride, 4.0 g. of m-anisidine and 10.0 ml. of triethylamine to the process of Example 14 and obtain thereby the title product, m.p. 172°-174° C.

Sources & evidence

ORD record
ord-92d9c5b3d55c4ef6b29918b3a554acd9
Source dataset
uspto-grants-1977_10
Patent number
US04053509

Reaction notes

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