Triethylamine → HCID 4319207, compound

HRID 972653Notes

Reaction equation

HRID 972653 reaction equation
[C:1]12([C:11](Cl)=[O:12])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[F:14][C:15]1[CH:16]=[C:17]([CH:19]=[CH:20][C:21]=1[F:22])[NH2:18].C(N(CC)CC)C>C(OCC)C>[F:14][C:15]1[CH:16]=[C:17]([NH:18][C:11]([C:1]23[CH2:10][CH:5]4[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]4)[CH2:2]2)[CH2:8]3)=[O:12])[CH:19]=[CH:20][C:21]=1[F:22]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 774693,4-DifluoroanilineHCID 989151-Adamantanecarbonyl chloride

Product 1

HCID 4319207HCID 4319207, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Subject 2.29 g. of adamantane carboxylic acid chloride (11.5 mmoles) 1.29 g. of (10 mmoles) 3,4-difluoroaniline and 4.0 ml. of triethylamine to the process of Example 11. Crystallize the residue obtained thereby from ethyl ether to yield the title product, m.p. 168.5°-170° C.

Workup

  1. customCrystallize the residue
  2. customobtained

Sources & evidence

ORD record
ord-4848297980a546e0a006587b0ada09af
Source dataset
uspto-grants-1977_10
Patent number
US04053509

Reaction notes

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