Propylamine → Isoquinoline

HRID 972730Notes

Reaction equation

HRID 972730 reaction equation
ClC(C)C(NC1C(OC)=C(OC)C=CC=1C[C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=[CH:11][N:10]=1)=O.C(N)CC>>[CH:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=[CH:11][N:10]=1

Participants

3

Reactant 2

HCID 7852PropylamineHCID 12369646HCID 12369646, compound

Product 1

HCID 8405Isoquinoline

Procedure

Following the procedure of Example 1, but reacting 1-(2-[2-chloro-propionyl] amino-3,4-dimethoxybenzyl) isoquinoline with n-propylamine, there is obtained 1-(2-[2-n-propylaminoprionyl] amino-3,4-dimethoxybenzyl) isoquinoline.

Sources & evidence

ORD record
ord-82a95599f09e407f920ab6ae4c2fa4db
Source dataset
uspto-grants-1977_10
Patent number
US04053603

Reaction notes

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