4H-Pyran-2-carboxylic acid, 5,6-dihydro-6,6-dimethyl-4-oxo- → HCID 15009971, compound

HRID 973783Notes

Reaction equation

HRID 973783 reaction equation
[CH3:1][C:2]1([CH3:12])[CH2:7][C:6](=[O:8])[CH:5]=[C:4]([C:9]([OH:11])=[O:10])[O:3]1.[H][H]>O1CCCC1.[C].[Pd]>[CH3:1][C:2]1([CH3:12])[CH2:7][C:6](=[O:8])[CH2:5][CH:4]([C:9]([OH:11])=[O:10])[O:3]1

Participants

5

Reactant 2

HCID 1985924H-Pyran-2-carboxylic acid, 5,6-dihydro-6,6-dimethyl-4-oxo-HCID 178418361HCID 178418361, compound

Product 1

HCID 15009971HCID 15009971, compound

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 8028TetrahydrofuranSolvent

Procedure

In 8 ml of tetrahydrofuran was dissolved 0.5 g of 3,4-dihydro-2,2-dimethyl-4-oxo-2H-pyran-6-carboxylic acid, followed by adding thereto 50 mg of 10% palladium-carbon, and the reaction was carried out with stirring in a hydrogen stream at room temperature for 3 hours.

Workup

  1. additionby adding

Sources & evidence

ORD record
ord-67862387d6b3465395834ac03926fa24
Source dataset
uspto-grants-1991_11
Patent number
US05064945

Reaction notes

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