Water → 4-[4,6-Bis(trichloromethyl)-1,3,5-triazin-2-yl]benzoic acid

HRID 973809Notes

Reaction equation

HRID 973809 reaction equation
[Cl:1][C:2]([Cl:23])([Cl:22])[C:3]1[N:8]=[C:7]([C:9]([Cl:12])([Cl:11])[Cl:10])[N:6]=[C:5]([C:13]2[CH:21]=[CH:20][C:16]([C:17](Cl)=[O:18])=[CH:15][CH:14]=2)[N:4]=1.[O:24]1CCCC1.O>C(N(CC)CC)C>[Cl:1][C:2]([Cl:22])([Cl:23])[C:3]1[N:8]=[C:7]([C:9]([Cl:11])([Cl:10])[Cl:12])[N:6]=[C:5]([C:13]2[CH:21]=[CH:20][C:16]([C:17]([OH:18])=[O:24])=[CH:15][CH:14]=2)[N:4]=1

Participants

5

Reactant 3

HCID 962WaterHCID 8028TetrahydrofuranHCID 14473251HCID 14473251, compound

Product 1

HCID 145729154-[4,6-Bis(trichloromethyl)-1,3,5-triazin-2-yl]benzoic acid

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

4-(4,6-Bis(trichloromethyl)-s-triazin-2-yl)-benzoyl chloride pw) is added to a mixture of tetrahydrofuran (10 pw) and water (5 pw). To complete the reaction, 1 pw of triethylamine is added after 6 minutes, and the mixture is stirred for another 10 minutes. The solvent is removed by distillation, and the residue is recrystallized from toluene/benzine. The product is identical with the compounds described in Examples 12 and 16.

Workup

  1. additionis added after 6 minutes
  2. customThe solvent is removed by distillation
  3. customthe residue is recrystallized from toluene/benzine

Sources & evidence

ORD record
ord-8b2fd8541db442ef8deba43357ee50f2
Source dataset
uspto-grants-1991_11
Patent number
US05064959

Reaction notes

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