Triethylamine → HCID 14479947, compound

HRID 973972Notes

Reaction equation

HRID 973972 reaction equation
[CH3:1][C:2]([C:5]1[CH:10]=[C:9]([SH:11])[CH:8]=[C:7]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:6]=1[OH:16])([CH3:4])[CH3:3].[CH2:17]([N:24]([CH:29]([CH3:31])[CH3:30])[C:25](=[O:28])[CH:26]=[CH2:27])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.C(N(CC)CC)C>CO>[CH3:4][C:2]([C:5]1[CH:10]=[C:9]([S:11][CH2:27][CH2:26][C:25]([N:24]([CH:29]([CH3:30])[CH3:31])[CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[O:28])[CH:8]=[C:7]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:6]=1[OH:16])([CH3:1])[CH3:3]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 703702,6-Di-tert-butyl-4-mercaptophenolHCID 22718852HCID 22718852, compound

Product 1

HCID 14479947HCID 14479947, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of 2,6-bis(1,1-dimethylethyl)-4-mercaptophenol (1.19 g, 5 mmole), N-benzyl-N-isopropyl-2-propenamide (1.0 g, 5 mmole) (prepared from acryloyl chloride and benzylisopropylamine), and triethylamine (0.05 ml) in methanol was stirred for 60 hours at room temperature. The reaction mixture was concentrated in vacuo to an oil. Chromatography on silica gel gave the title compound.

Workup

  1. concentrationThe reaction mixture was concentrated in vacuo to an oil

Sources & evidence

ORD record
ord-7a7aac450e104d1b95f5f0552a1b2b96
Source dataset
uspto-grants-1991_11
Patent number
US05066679

Reaction notes

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