Isopropanol → HCID 54297882, compound

HRID 974321Notes

Reaction equation

HRID 974321 reaction equation
Cl.[CH3:2][C:3]1[CH:4]=[CH:5][C:6]([CH:9]=[CH:10][CH2:11]Cl)=[N:7][CH:8]=1.[NH2:13][C:14]1[S:15][C:16]2[CH2:17][CH2:18][NH:19][CH2:20][CH2:21][C:22]=2[N:23]=1.C(O)(C)C>C(Cl)(Cl)Cl>[NH2:13][C:14]1[S:15][C:16]2[CH2:17][CH2:18][N:19]([CH2:11][CH:10]=[CH:9][C:6]3[CH:5]=[CH:4][C:3]([CH3:2])=[CH:8][N:7]=3)[CH2:20][CH2:21][C:22]=2[N:23]=1

Participants

5

Reactant 3

HCID 3776IsopropanolHCID 199857852-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepineHCID 70048082HCID 70048082, compound

Product 1

HCID 54297882HCID 54297882, compoundYield 22%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Prepared from 3-(5-methyl-2-pyridyl)allyl chloride hydrochloride and 3 equivalents of 2-amino-4,5,7,8-tetrahydro-6H-thiazolo[5,4-d]azepine in chloroform. Yield: 22% of theory, Melting point: 172°-175° C. (isopropanol).

Sources & evidence

ORD record
ord-0853bf1f0b8e4fb396603f91da2a20c5
Source dataset
uspto-grants-1991_11
Patent number
US05068325

Reaction notes

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