Lithium diisopropylamide → HCID 178505776, compound

HRID 974404Notes

Reaction equation

HRID 974404 reaction equation
[Cl-].[Cl-].[CH:3]1([Ti+2:8][CH:9]2[CH:13]=[CH:12][CH:11]=[CH:10]2)[CH:7]=[CH:6][CH:5]=[CH:4]1.[F:14][C:15]1[CH:20]=[C:19]([F:21])[CH:18]=[CH:17][C:16]=1[CH2:22][N:23]1[CH:27]=[CH:26][CH:25]=[CH:24]1.[CH:28]([N-:31][CH:32]([CH3:34])C)([CH3:30])C.[Li+]>>[CH:9]1([Ti:8]([CH:3]2[CH:4]=[CH:5][CH:6]=[CH:7]2)([C:20]2[C:19]([F:21])=[CH:18][CH:17]=[C:16]([CH2:22][N:31]3[CH:28]=[CH:30][CH:34]=[CH:32]3)[C:15]=2[F:14])[C:20]2[C:19]([F:21])=[CH:18][CH:17]=[C:16]([CH2:22][N:23]3[CH:27]=[CH:26][CH:25]=[CH:24]3)[C:15]=2[F:14])[CH:13]=[CH:12][CH:11]=[CH:10]1

Participants

4

Reactant 3

HCID 2724682Lithium diisopropylamideHCID 189723601-[(2,4-Difluorophenyl)methyl]-1H-pyrroleHCID 178420582HCID 178420582, compound

Product 1

HCID 178505776HCID 178505776, compoundYield 55.1%

Procedure

Analogously to Example 19,2.5 g (0.010 mol)of bis(cyclopentadienyl)titanium dichloride and 4.25 g (0.022 mol) of 1-[(2,4-difluorophenyl)methyl]-1H-pyrrole are reacted with 0.022 mol of lithium diisopropylamide solution. 3.1 g of orange crystals melting point 192°-194° C. are obtained.

Sources & evidence

ORD record
ord-291c0c3be6c6497bad6f6ee6a6bc1bdf
Source dataset
uspto-grants-1991_11
Patent number
US05068371

Reaction notes

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