Sodium Hydroxide → Glyphosate
反応式
C[CH:2]([C:14]([OH:16])=[O:15])[N:3]([CH2:7][P:8]([O:12]C)([O:10]C)=[O:9])C(C)C.[OH-].[Na+]>O>[P:8]([CH2:7][NH:3][CH2:2][C:14]([OH:16])=[O:15])([OH:12])([OH:10])=[O:9]参加物
4
反応条件
- 温度
- 300 °C
実験手順
To a pressure reactor was added 2.09 g (8.3 mmol) of methyl-N-[(dimethoxyphosphinyl)methyl]-N-isopropylglycine, 2.17 g (27.2 mmol) of 50% sodium hydroxide, and 10 ml of water. The reactor vessel was flushed with nitrogen for 15 minutes, sealed, and heated to 300° C. for 3.5 hours while the pressure was controlled to maintain water within the reactor. After cooling and release of residual pressure, the reaction mixture was removed from the reactor and diluted with 5 ml of water. This solution was acidified by the addition of 2.4 ml of hydrochloric acid and purified by ion-exchange chromatography to provide 0.27 g (20% yield) of N-phosphonomethylglycine.
後処理
- customThe reactor vessel was flushed with nitrogen for 15 minutes
- customsealed
- temperatureto maintain water within the reactor
- temperatureAfter cooling
- customrelease of residual pressure, the reaction mixture was removed from the reactor
- additiondiluted with 5 ml of water
- additionThis solution was acidified by the addition of 2.4 ml of hydrochloric acid
- custompurified by ion-exchange chromatography
出典と根拠
- ORDレコード
- ord-6d89b449551549f3a9f819392ec770ca
- 出典データセット
- uspto-grants-1991_11
- 特許番号
- US05068404
反応ノート
読み込み中…