huagongshe.com
HRID975186

反应详情

EQUATION

反应方程式

HRID 975186 的结构方程式

REACTANTS

反应物

3
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：[Na+].[OH-]
HCID14798

Sodium Hydroxide

HNaO

结构：Cc1cn([C@@H]2O[C@H](C(O)S(C)(=O)=O)[C@](O)(S(C)(=O)=O)[C@]2(O)S(C)(=O)=O)c(=O)[nH]c1=O
HCID53689434

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cn([C@@H]2O[C@H](C(O)S(C)(=O)=O)[C@H]3O[C@H]32)c(=O)[nH]c1=O
HCID86750434

未命名化合物

CONDITIONS

反应条件

温度
0 °C

PROCEDURE

实验过程

To a solution of 49 ml 1N sodium hydroxide was added 2',3',5'-tris(methanesulfonyl)-5-methyluridine (2, 6.0 g). The mixture was stirred at 70°-72° C. for 15 minutes and then cooled 0° C. The pH was adjusted to 4 by using concentrated HCl. The resulting slurry was filtered, washed with 2×10 ml water and dried to give 5'-methanesulfonyl-2'-3'-anhydro-5-methyluridine (3), 3.1 g, (84%).

WORKUP

后处理

  1. filtrationThe resulting slurry was filtered
  2. washwashed with 2×10 ml water
  3. customdried