Methylamine → Methyl-carbamic acid 2-[4-amino-5-(5-chloro-2-isopropyl-4-methoxy-phenoxy)-pyrimidin-2-ylamino]-propyl ester

HRID 97595Notes

Reaction equation

HRID 97595 reaction equation
[CH2:28]1[CH2:31][CH2:30][CH2:29][O:32]1.[CH3:26][NH2:27].[NH2:1][c:2]1[n:3][c:4]([NH:21][CH:22]([CH2:23][OH:24])[CH3:25])[n:5][cH:6][c:7]1[O:8][c:9]1[c:10]([CH:18]([CH3:19])[CH3:20])[cH:11][c:12]([O:16][CH3:17])[c:13]([Cl:15])[cH:14]1>>[NH2:1][c:2]1[n:3][c:4]([NH:21][CH:22]([CH2:23][O:24][C:28]([NH:27][CH3:26])=[O:32])[CH3:25])[n:5][cH:6][c:7]1[O:8][c:9]1[c:10]([CH:18]([CH3:19])[CH3:20])[cH:11][c:12]([O:16][CH3:17])[c:13]([Cl:15])[cH:14]1

Participants

4

Reactant 3

HCID 6329MethylamineHCID 8028TetrahydrofuranHCID 670534302-[[4-Amino-5-(5-chloro-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]propan-1-ol

Product 1

HCID 16119173Methyl-carbamic acid 2-[4-amino-5-(5-chloro-2-isopropyl-4-methoxy-phenoxy)-pyrimidin-2-ylamino]-propyl ester

Sources & evidence

ORD record
ord-550cf865ea424f83ac194a918aa8a1f0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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