huagongshe.com
HRID976030

反应详情

EQUATION

反应方程式

HRID 976030 的结构方程式

REACTANTS

反应物

3
结构：O=P([O-])([O-])[O-]
HCID1061

Phosphate

O4P-3

结构：Cc1ccc(S(=O)(=O)O)cc1
HCID6101

4-Methylbenzenesulfonic acid

C7H8O3S

结构：C/C=C/[C@H]1O[C@@H]([C@@H](C)[C@H](O)[C@H](C)[C@H]2OC(=O)/C(OC)=C/C(C)=C/[C@@H](C)[C@@H](O)[C@@H](CC)[C@@H](O)[C@H](C)C/C(C)=C/C=C/[C@@H]2OC)C[C@@H](O[C@H]2C[C@@H](O)[C@H](OC(N)=O)[C@@H](C)O2)[C@@H]1C
HCID11115550

未命名化合物

PRODUCTS

生成物

1
结构：C/C=C/[C@H]1O[C@@H]([C@@H](C)[C@H](O)[C@H](C)[C@H]2OC(=O)/C(OC)=C/C(C)=C/[C@@H](C)[C@@H](O)[C@@H](CC)[C@@H](O)[C@H](C)C/C(C)=C/C=C/[C@@H]2OC)C[C@@H](O)[C@@H]1C
HCID11072454

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：Cl
溶剂HCID313

Hydrochloric Acid

ClH

结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

500 mg (2.6 mmol, 22.5 equiv.) of toluene-4-sulfonic acid in 3 ml of 1N HCl are added to a solution of 100 mg of 21-deoxyconcanamycin A (0.117 mmol) in 15 ml of MeOH and the reaction mixture is stirred for 48 hours at room temperature. After the addition of 20 ml of phosphate buffer (pH=7) the solvent is removed in vacuo. Standard working-up, followed by column chromatography on silica gel (system E then system D), yields the title compound. M.p. 104° C.

WORKUP

后处理

  1. customis removed in vacuo