反应详情

Hydrochloric acid gas is piped for an hour over a solution of 59.4 g of tert.butyl (trans-4-aminocyclohexyl)oxyacetate in 500 ml of methanol, cooled in an ice bath, and then the mixture is stirred overnight at ambient temperature. It is evaporated to dryness, the residue is triturated with acetone and the solid is suction filtered and dried.

1. temperaturecooled in an ice bath
2. customIt is evaporated to dryness
3. customthe residue is triturated with acetone
4. filtrationfiltered
5. customdried