Propionic anhydride → HCID 12637080, compound

HRID 976487Notes

Reaction equation

[C:1]1([C:7]2[CH:14]=[CH:13][C:10]([CH:11]=O)=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:15]([O:19]C(=O)CC)(=[O:18])[CH2:16][CH3:17]>>[CH3:17]/[C:16](=[CH:11]\[C:10]1[CH:13]=[CH:14][C:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)=[CH:8][CH:9]=1)/[C:15]([OH:19])=[O:18]

Participants

Reactant 2

HCID 31263Propionic anhydride

HCID 76689(1,1'-Biphenyl)-4-carboxaldehyde

Product 1

HCID 12637080HCID 12637080, compoundYield 49%

Procedure

The procedure is performed in an analogous manner to that described in Example 17 (step A), starting from 4-phenylbenzaldehyde and using 6 equivalents of propionic anhydride. Yield: 49% m.p. 178° C. IR (nujol): 1670 cm-1 1H NMR (CDCl3 /TMS): 11.50 to 11.20 (broad s, 1H); 7.70 (s, 1H); 7.60 to 7.20 (m, 9H); 2.15 (s, 3H).

Sources & evidence

ORD record: ord-74251c5b0f5541ee810a9694f612ce2d
Source dataset: uspto-grants-1997_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05612371

Reaction notes

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