2-Hydroxy-1,2,3-propanetricarboxylic acid hydrate (1:1) → Tricalcium Citrate

HRID 978327Notes

Reaction equation

HRID 978327 reaction equation
[O-2].[Ca+2:2].O.[C:4]([OH:16])(=[O:15])[CH2:5][C:6]([CH2:11][C:12]([OH:14])=[O:13])([C:8]([OH:10])=[O:9])[OH:7]>O>[C:4]([O-:16])(=[O:15])[CH2:5][C:6]([CH2:11][C:12]([O-:14])=[O:13])([C:8]([O-:10])=[O:9])[OH:7].[Ca+2:2].[C:4]([O-:16])(=[O:15])[CH2:5][C:6]([CH2:11][C:12]([O-:14])=[O:13])([C:8]([O-:10])=[O:9])[OH:7].[Ca+2:2].[Ca+2:2]

Participants

4

Reactant 2

HCID 222302-Hydroxy-1,2,3-propanetricarboxylic acid hydrate (1:1)HCID 6850728Calciumoxide

Product 1

HCID 13136Tricalcium Citrate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
90 °C

Procedure

An aqueous calcium citrate mixture was prepared by adding 28 grams of calcium oxide to 210 grams of citric acid monohydrate in 476 grams of distilled water. To this, 11.0 grams of acetaldehyde/diacetyl flavorant was added. Some of the mixture precipitated out of solution. The mixture was then blended at high speed in a Waring blender for approximately two minutes, and then transferred to a Niro dryer. The dryer was maintained with an inlet temperature of 120° C. and an outlet temperature of 90° C. Gas chromographic analysis of the resultant powder indicates that there was no fixation or retention of the acetaldehyde/diacetyl flavorant after spray-drying.

Workup

  1. additionTo this, 11.0 grams of acetaldehyde/diacetyl flavorant was added
  2. customSome of the mixture precipitated out of solution
  3. customafter spray-drying

Sources & evidence

ORD record
ord-d7995dd8a0784cd2810db215f03d433e
Source dataset
uspto-grants-1987_05
Patent number
US04664920

Reaction notes

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