Ethanol → HCID 13576359, compound

HRID 979030Notes

Reaction equation

HRID 979030 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]1[O:11][C:9](=O)[C:8](=C=O)[CH2:7]1.O.[NH2:15][NH2:16].[CH2:17]([OH:19])C>>[O:11]1[CH:9]=[CH:8][CH:7]=[C:6]1[C:2]1[CH:3]([CH2:17][OH:19])[CH2:4][C:5](=[O:1])[NH:15][N:16]=1

Participants

4

Reactant 3

HCID 702EthanolHCID 24654Hydrazine hydrate (1:1)HCID 86741509HCID 86741509, compound

Product 1

HCID 13576359HCID 13576359, compound

Conditions

Temperature
50 °C

Procedure

4.7 g (0.026 mol) of 4-(2-furyl)-carbonyl-γ-butyrolactone and 1.5 ml (0.03 mol) of hydrazine hydrate are dissolved in 40 ml of ethanol at room temperature and stirred at 50° C. for 1 hour. After the mixture has been concentrated, the reaction product is subjected to fractionation by chromatography over a silica gel column using methylene chloride/methanol=9:1 as the mobile phase.

Workup

  1. concentrationAfter the mixture has been concentrated

Sources & evidence

ORD record
ord-57fa37f41e6d4fa0a18ba98839dafcae
Source dataset
uspto-grants-1987_05
Patent number
US04666902

Reaction notes

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