Hydrazine hydrate (1:1) → HCID 178422930, compound

HRID 979190Notes

Reaction equation

HRID 979190 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([C:11]2[N:12]=[CH:13][NH:14][CH:15]=2)[CH:5]=[CH:6][C:7]=1[N+:8]([O-])=O.O.NN>CO>[CH3:1][C:2]1[CH:3]=[C:4]([C:11]2[N:12]=[CH:13][NH:14][CH:15]=2)[CH:5]=[CH:6][C:7]=1[NH2:8]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 178422932HCID 178422932, compound

Product 1

HCID 178422930HCID 178422930, compoundYield 100.7%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

4-(3-Methyl-4-nitrophenyl)-1-H-imidazole (9.2 g) was allowed to react with 85% hydrazine hydrate in methanol to give 7.9 g of 4-(3-methyl-4-aminophenyl)-1-H-imidazole, M.p. 195°-197° C. 4-(3-Methoxy-4-aminophenyl)-1-H-imidazole, M.p. 145° C. (dec.), was prepared analogously.

Sources & evidence

ORD record
ord-91fe6d01ed704010af0a529ea394a7ce
Source dataset
uspto-grants-1987_05
Patent number
US04666932

Reaction notes

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