反应详情

A solution of 4-fluoro-2-methoxyphenol (27.0 g) in DMF (50 ml) was added dropwise to a mixture of 60% NaH (7.0 g) in DMF (250 ml). After stirring the reaction for 1 hour, allylbromide (21.0 ml) was added and stirring was continued for 1 hour at room temperature. The reaction was poured onto ice/water and extracted with ethyl acetate. The organic layer was separated, dried and evaporated to afford the desired compound.

1. customthe reaction for 1 hour
2. stirringstirring
3. additionThe reaction was poured onto ice/water
4. extractionextracted with ethyl acetate
5. customThe organic layer was separated
6. customdried
7. customevaporated