Sulfate Ion → H 142-08

HRID 980163Notes

Reaction equation

HRID 980163 reaction equation
S([O-])([O-])(=O)=O.[NH2:6][CH2:7][CH2:8][NH:9][C:10]([N:12]1[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1)=[O:11].[CH3:18][CH:19]([CH3:36])[CH2:20][O:21][CH2:22][CH2:23][O:24][C:25]1[CH:35]=[CH:34][C:28]([O:29][CH:30]2[O:33][CH:31]2[CH3:32])=[CH:27][CH:26]=1>>[OH:33][CH:31]([CH2:30][O:29][C:28]1[CH:34]=[CH:35][C:25]([O:24][CH2:23][CH2:22][O:21][CH2:20][CH:19]([CH3:36])[CH3:18])=[CH:26][CH:27]=1)[CH2:32][NH:6][CH2:7][CH2:8][NH:9][C:10]([N:12]1[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1)=[O:11]

Participants

4

Reactant 3

HCID 1117Sulfate IonHCID 11041198N-(2-Aminoethyl)-4-morpholinecarboxamideHCID 867412084-(2-(2-Methylpropoxy)ethoxy)phenoxy-1,2-epoxypropane

Product 1

HCID 132688H 142-08

Procedure

N-(2-((2-hydroxy-3-(4-(2-(2-methylpropoxy)ethoxy)phenoxy)propyl)amino)ethyl)-4-morpholinecarboxamide was prepared in accordance with example 4 using 10.1 g of the neutral sulphate of N-2-aminoethyl-4-morpholinecarboxamide and 9.3 g of 3-(4-(2-(2-methylpropoxy)ethoxy)phenoxy-1,2-epoxypropane as starting materials. Yield 3.9 g. Melting point 95°-96° C. (base). The structure was determined using NMR-analysis.

Sources & evidence

ORD record
ord-175129d99d69472388166a067bfe375b
Source dataset
uspto-grants-1987_01
Patent number
US04636501

Reaction notes

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