Methylamine → HCID 67893862, compound

HRID 981552Notes

Reaction equation

HRID 981552 reaction equation
[CH:1](=O)[C:2]1[CH:7]=[CH:6][CH:5]=[N:4][CH:3]=1.[CH3:9][NH2:10]>C1(C)C=CC=CC=1>[CH:1](=[CH:9][NH2:10])[C:2]1[CH:7]=[CH:6][CH:5]=[N:4][CH:3]=1

Participants

4

Reactant 2

HCID 6329MethylamineHCID 103713-Pyridinecarboxaldehyde

Product 1

HCID 67893862HCID 67893862, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Nicotinaldehyde (10.7 g, 0.1 mol) was dissolved in toluene (100 ml). A 40% aqueous methylamine (23.3 g, 0.3 mol) solution was added. This mixture was subjected to azeotropic dehydration for 3 hours. The product mixture was concentrated under reduced pressure, giving N-nicotinylidenemethylamine (11.7 g, 98% yield)

Workup

  1. concentrationThe product mixture was concentrated under reduced pressure

Sources & evidence

ORD record
ord-374324b7e72f451f973e880d7a0a1860
Source dataset
uspto-grants-1991_02
Patent number
US04992455

Reaction notes

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