Water → Methyl 2-[4-{2-(4-chlorophenyl)-5-(2-oxopyrrolidin-1-yl)benzyloxy}-2-fluorophenyl]-1-cyclohexylbenzimidazole-5-carboxylate
Reaction equation
[CH3:43][CH2:44][N:45]([CH2:46][CH3:47])[CH2:48][CH3:49].[CH:58]([Cl:59])([Cl:60])[Cl:61].[Cl:50][CH2:51][CH2:52][CH2:53][C:54](=[O:55])[Cl:56].[NH2:1][c:2]1[cH:3][cH:4][c:5](-[c:36]2[cH:37][cH:38][c:39]([Cl:42])[cH:40][cH:41]2)[c:6]([CH2:7][O:8][c:9]2[cH:10][c:11]([F:34])[c:12](-[c:15]3[n:16][c:17]4[c:18]([n:19]3[CH:20]3[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]3)[cH:26][cH:27][c:28]([C:30](=[O:31])[O:32][CH3:33])[cH:29]4)[cH:13][cH:14]2)[cH:35]1.[OH2:57]>>[N:1]1([c:2]2[cH:3][cH:4][c:5](-[c:36]3[cH:37][cH:38][c:39]([Cl:42])[cH:40][cH:41]3)[c:6]([CH2:7][O:8][c:9]3[cH:10][c:11]([F:34])[c:12](-[c:15]4[n:16][c:17]5[c:18]([n:19]4[CH:20]4[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]4)[cH:26][cH:27][c:28]([C:30](=[O:31])[O:32][CH3:33])[cH:29]5)[cH:13][cH:14]3)[cH:35]2)[CH2:51][CH2:52][CH2:53][C:54]1=[O:55]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-68b4189f016c42f8b279677250f4d69a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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