Dimethylthiocarbamoyl chloride → HCID 20068249, compound

HRID 982546Notes

Reaction equation

HRID 982546 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([C:9]([C:11]2[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=2)=[O:10])[CH:6]=[CH:7][CH:8]=1)#[N:2].[CH3:18][N:19]([CH3:23])[C:20](Cl)=[S:21]>>[CH3:18][N:19]([CH3:23])[C:20](=[S:21])[O:17][C:14]1[CH:13]=[CH:12][C:11]([C:9](=[O:10])[C:5]2[CH:6]=[CH:7][CH:8]=[C:3]([C:1]#[N:2])[CH:4]=2)=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 27871Dimethylthiocarbamoyl chlorideHCID 14622766HCID 14622766, compound

Product 1

HCID 20068249HCID 20068249, compoundYield 93.2%

Procedure

Following the procedure described in Preparation I and starting from 27 g (0.121 mol) of 3-cyanophenyl 4-hydroxyphenyl methanone and 17.2 g (0.138 mol) of dimethylthiocarbamoyl chloride, 35 g (yield: 88%) of O-4-(3-cyanobenzoyl)phenyl dimethylthiocarbamate melting at 160° C. are obtained.

Workup

  1. customdescribed in Preparation I

Sources & evidence

ORD record
ord-820dd569ecd24e68869f0b60b281c246
Source dataset
uspto-grants-1991_02
Patent number
US04996347

Reaction notes

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