Water → HCID 6410643, compound

HRID 985938Notes

Reaction equation

HRID 985938 reaction equation
Cl[C:2]1[N:3]=[N:4][C:5]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:6][C:7]=1[CH3:8].[CH3:15][O:16][CH2:17][CH2:18][NH2:19].O>C(O)CCC>[CH3:15][O:16][CH2:17][CH2:18][NH:19][C:2]1[N:3]=[N:4][C:5]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:6][C:7]=1[CH3:8]

Participants

5

Reactant 3

HCID 962WaterHCID 80182-MethoxyethylamineHCID 1199993-Chloro-4-methyl-6-phenylpyridazine

Product 1

HCID 6410643HCID 6410643, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

A mixture of 7 g of 3-chloro 4-methyl 6-phenyl pyridazine and 7 g of 2-methoxy ethylamine in 50 ml of butanol is taken to reflux for 4 days. The hot solution is poured into 200 ml of water and extracted with ethyl acetate. The organic solution is dried over magnesium sulfate then evaporated to dryness.

Workup

  1. temperatureto reflux for 4 days
  2. extractionextracted with ethyl acetate
  3. dry with materialThe organic solution is dried over magnesium sulfate
  4. customthen evaporated to dryness

Sources & evidence

ORD record
ord-e602df8abd8e4825ae7ea9a34796eb20
Source dataset
uspto-grants-1987_12
Patent number
US04710499

Reaction notes

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