Benzylamine → HCID 51056108, compound

HRID 985965Notes

Reaction equation

HRID 985965 reaction equation
O=[CH:2][C@@H:3]([C@H:5]([C@@H:7]([C@@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])[OH:4].[CH2:13]([NH2:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C(O)C>[CH2:13]([NH:20][C@@H:2]1[O:10][C@H:9]([CH2:11][OH:12])[C@@H:7]([OH:8])[C@H:5]([OH:6])[C@H:3]1[OH:4])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

4

Reactant 2

HCID 7504BenzylamineHCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

Product 1

HCID 51056108HCID 51056108, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

50 g of D-glucose were dissolved in 1,000 ml of hot ethanol and, after addition of 89 g of benzylamine, the mixture was left at room temperature for 48 hours. It was then cooled with ice and the product was precipitated with petroleum ether. The product was filtered off with suction, washed with ether and dried in vacuo. 1H-NMR in CD3OD: δ=7.33, broad singlet, phenyl-H.

Workup

  1. temperatureIt was then cooled with ice
  2. customthe product was precipitated with petroleum ether
  3. filtrationThe product was filtered off with suction
  4. washwashed with ether
  5. customdried in vacuo

Sources & evidence

ORD record
ord-d3eccdd5b6754f33ba9bab80a7205778
Source dataset
uspto-grants-1987_12
Patent number
US04710491

Reaction notes

Loading…