Iodine → HCID 20159245, compound

HRID 986085Notes

Reaction equation

HRID 986085 reaction equation
[F:1][C:2]([F:18])([F:17])[C:3]1[CH:4]=[C:5]2[C:14](=[CH:15][CH:16]=1)[NH:13][C:12]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[S:6]2.[C:19](#[N:23])[CH2:20][C:21]#[N:22].C([O-])(=O)C.[K+].II>CO>[F:18][C:2]([F:1])([F:17])[C:3]1[CH:4]=[C:5]2[C:14](=[CH:15][CH:16]=1)[N:13]=[C:12]1[C:7](=[CH:8][C:9](=[C:20]([C:19]#[N:23])[C:21]#[N:22])[CH:10]=[CH:11]1)[S:6]2

Participants

6

Reactant 4

HCID 807IodineHCID 8010MalononitrileHCID 2428443-(trifluoromethyl)-10H-phenothiazineHCID 517044Potassium Acetate

Product 1

HCID 20159245HCID 20159245, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

To a stirred solution of 2.6 g 7-trifluoromethylphenothiazine, 1 g malononitrile and 4 g potassium acetate in 70 ml methanol was added a solution of 4 g iodine in 50 ml methanol. The precipitated dye was filtered, washed repeatedly with methanol and recrystallised in chloroform-methanol. Yield 0.6 g (18%).

Workup

  1. filtrationThe precipitated dye was filtered
  2. washwashed repeatedly with methanol
  3. customrecrystallised in chloroform-methanol

Sources & evidence

ORD record
ord-d312167e654c463d93b0c996af2d0c6a
Source dataset
uspto-grants-1987_12
Patent number
US04710570

Reaction notes

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