4-Toluenesulfonyl chloride → 1,5-Pentanediol monotosylate

HRID 986183Notes

Reaction equation

HRID 986183 reaction equation
[CH2:1]([OH:7])[CH2:2][CH2:3][CH2:4][CH2:5][OH:6].[S:8](Cl)([C:11]1[CH:17]=[CH:16][C:14]([CH3:15])=[CH:13][CH:12]=1)(=[O:10])=[O:9]>>[S:8]([O:6][CH2:5][CH2:4][CH2:3][CH2:2][CH2:1][OH:7])([C:11]1[CH:17]=[CH:16][C:14]([CH3:15])=[CH:13][CH:12]=1)(=[O:10])=[O:9]

Participants

3

Reactant 2

HCID 73974-Toluenesulfonyl chlorideHCID 81051,5-Pentanediol

Product 1

HCID 114595781,5-Pentanediol monotosylate

Procedure

By following a procedure of Reference Example 1, 6.2 g (60 mmole) of 1,5-pentanediol and 5.7 g (30 mmole) of tosyl chloride were treated to give 1,5-pentanediol monotosylate as a colorless oily material Yield 4.1 g (yield: 53%).

Workup

  1. additionwere treated

Sources & evidence

ORD record
ord-91f8b9d62de140fa8bde8c3307098ce0
Source dataset
uspto-grants-1987_12
Patent number
US04710579

Reaction notes

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