Phosphoric Acid → HCID 178446269, compound

HRID 986221Notes

Reaction equation

HRID 986221 reaction equation
[C:1]1([CH:7]([CH2:20][CH2:21][CH3:22])[CH2:8][NH:9][C:10]2[N:15]=[C:14]([CH3:16])[C:13]([O:17][CH3:18])=[C:12](C)[N:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[P:23](=[O:27])([OH:26])([OH:25])[OH:24].[CH:28](O)(C)C>>[P:23]([OH:27])([OH:26])([OH:25])=[O:24].[C:1]1([CH:7]([CH2:20][CH2:21][CH3:22])[CH2:8][NH:9][C:10]2[N:11]=[CH:12][C:13]([CH3:28])([O:17][CH3:18])[CH:14]([CH3:16])[N:15]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 3

HCID 1004Phosphoric AcidHCID 3776IsopropanolHCID 20158316HCID 20158316, compound

Product 1

HCID 178446269HCID 178446269, compound

Conditions

Temperature
0 °C

Procedure

1.09 g of 2-phenylpentylamino-4,6-dimethyl-5-methoxypyrimidine was dissolved in 15 ml isopropylalcohol and cooled to 0° C. Phosphoric acid (85%, 9 g) was added and the mixture stirred at 0° C. for 30 minutes. White solid precipitated and was collected after removal of the isopropylalcohol, washing with pentane and drying in vacuo at 45° C. M.p.: 107°-8° C.

Workup

  1. customWhite solid precipitated
  2. customwas collected
  3. customafter removal of the isopropylalcohol
  4. washwashing with pentane
  5. customdrying in vacuo at 45° C

Sources & evidence

ORD record
ord-17efe1707f0747f7b837f165e5cd1033
Source dataset
uspto-grants-1987_12
Patent number
US04711888

Reaction notes

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