Thioglycolic Acid → [[2-[(2'-Hydroxy[1,1':3',1"-terphenyl]-5'-yl)thio]ethyl]thio]acetic acid

HRID 986302Notes

Reaction equation

HRID 986302 reaction equation
[SH:1][CH2:2][C:3]([OH:5])=[O:4].Br[CH2:7][CH2:8]Cl.[Na].[SH:11][C:12]1[CH:13]=[C:14]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[C:15]([OH:24])=[C:16]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:17]=1>>[OH:24][C:15]1[C:16]([C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)=[CH:17][C:12]([S:11][CH2:7][CH2:8][S:1][CH2:2][C:3]([OH:5])=[O:4])=[CH:13][C:14]=1[C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1

Participants

5

Reactant 4

HCID 1133Thioglycolic AcidHCID 78491-Bromo-2-ChloroethaneHCID 5360545SodiumHCID 149891685'-Mercapto[1,1':3',1"-terphenyl]-2'-ol

Product 1

HCID 14011811[[2-[(2'-Hydroxy[1,1':3',1"-terphenyl]-5'-yl)thio]ethyl]thio]acetic acid

Procedure

The title compound was prepared according to the method of Example 13 from mercaptoacetic acid (2.3 g, 0.025 mole); 1-bromo-2-chloroethane (2.1 ml, 0.025 mole); sodium (1.8 g, 0.08 mole) and 5'-mercapto-[1,1':3',1"-terphenyl]-2'-ol (8.6 g, 0.03 mole), m.p. ca. 125° C.

Sources & evidence

ORD record
ord-a2cc8d1f17f5444084a4911da313f9d7
Source dataset
uspto-grants-1987_12
Patent number
US04711903

Reaction notes

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