Ethyl Acetate → HCID 15228813, compound

HRID 986733Notes

Reaction equation

HRID 986733 reaction equation
COC(=O)C(CC(OC(C)(C)C)=O)=C.C[O:16][P:17]([CH:33]([NH:35]C(OCC1C=CC=CC=1)=O)[CH3:34])([CH2:19][CH:20]([C:29]([O:31]C)=[O:30])[CH2:21][C:22]([O:24]CCCC)=[O:23])=[O:18].C(OCC)(=O)C>C(#N)C>[NH2:35][CH:33]([P:17]([CH2:19][CH:20]([C:29]([OH:31])=[O:30])[CH2:21][C:22]([OH:24])=[O:23])(=[O:16])[OH:18])[CH3:34]

Participants

5

Reactant 3

HCID 8857Ethyl AcetateHCID 181731654-tert-Butyl 1-methyl 2-methylidenebutanedioateHCID 19880118HCID 19880118, compound

Product 1

HCID 15228813HCID 15228813, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

By methods used in Example 2 and employing methyl-2-t-butoxycarbonylmethylacrylate was prepared methyl-1-benzyloxycarbonylaminoethyl-[2-carbomethoxy-3-butoxycarbonyl-1-propyl]phosphinate. TLC (silica, 9:1, ethyl acetate:acetonitrile) Rf =0.58.

Sources & evidence

ORD record
ord-161b50b882f045bea1588105b1a79904
Source dataset
uspto-grants-1987_12
Patent number
US04715994

Reaction notes

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