Sodium Hydroxide → HCID 136388360, compound

HRID 987354Notes

Reaction equation

HRID 987354 reaction equation
C([O:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][O:17][C:18]1[CH:23]=[CH:22][C:21]([C:24]2[C:25]3[NH:29][C:28]([C:30]([C:126]4[CH:131]=[C:130]([O:132][CH2:133][CH2:134][CH2:135][CH2:136][CH2:137][CH2:138][CH2:139][CH2:140][CH2:141][CH3:142])[C:129]([O:143][CH2:144][CH2:145][CH2:146][CH2:147][CH2:148][CH2:149][CH2:150][CH2:151][CH2:152][CH3:153])=[C:128]([O:154][CH2:155][CH2:156][CH2:157][CH2:158][CH2:159][CH2:160][CH2:161][CH2:162][CH2:163][CH3:164])[CH:127]=4)=[C:31]4[N:125]=[C:34]([C:35]([C:86]5[CH:91]=[C:90]([O:92][CH2:93][CH2:94][CH2:95][CH2:96][CH2:97][CH2:98][CH2:99][CH2:100][CH2:101][CH3:102])[C:89]([O:103][CH2:104][CH2:105][CH2:106][CH2:107][CH2:108][CH2:109][CH2:110][CH2:111][CH2:112][CH3:113])=[C:88]([O:114][CH2:115][CH2:116][CH2:117][CH2:118][CH2:119][CH2:120][CH2:121][CH2:122][CH2:123][CH3:124])[CH:87]=5)=[C:36]5[NH:85][C:39](=[C:40]([C:46]6[CH:51]=[C:50]([O:52][CH2:53][CH2:54][CH2:55][CH2:56][CH2:57][CH2:58][CH2:59][CH2:60][CH2:61][CH3:62])[C:49]([O:63][CH2:64][CH2:65][CH2:66][CH2:67][CH2:68][CH2:69][CH2:70][CH2:71][CH2:72][CH3:73])=[C:48]([O:74][CH2:75][CH2:76][CH2:77][CH2:78][CH2:79][CH2:80][CH2:81][CH2:82][CH2:83][CH3:84])[CH:47]=6)[C:41]6[CH:42]=[CH:43][C:44]=2[N:45]=6)[CH:38]=[CH:37]5)[CH:33]=[CH:32]4)=[CH:27][CH:26]=3)=[CH:20][CH:19]=1)(=O)C.[OH-].[Na+]>C1COCC1>[OH:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][O:17][C:18]1[CH:19]=[CH:20][C:21]([C:24]2[C:25]3[NH:29][C:28]([C:30]([C:126]4[CH:131]=[C:130]([O:132][CH2:133][CH2:134][CH2:135][CH2:136][CH2:137][CH2:138][CH2:139][CH2:140][CH2:141][CH3:142])[C:129]([O:143][CH2:144][CH2:145][CH2:146][CH2:147][CH2:148][CH2:149][CH2:150][CH2:151][CH2:152][CH3:153])=[C:128]([O:154][CH2:155][CH2:156][CH2:157][CH2:158][CH2:159][CH2:160][CH2:161][CH2:162][CH2:163][CH3:164])[CH:127]=4)=[C:31]4[N:125]=[C:34]([C:35]([C:86]5[CH:91]=[C:90]([O:92][CH2:93][CH2:94][CH2:95][CH2:96][CH2:97][CH2:98][CH2:99][CH2:100][CH2:101][CH3:102])[C:89]([O:103][CH2:104][CH2:105][CH2:106][CH2:107][CH2:108][CH2:109][CH2:110][CH2:111][CH2:112][CH3:113])=[C:88]([O:114][CH2:115][CH2:116][CH2:117][CH2:118][CH2:119][CH2:120][CH2:121][CH2:122][CH2:123][CH3:124])[CH:87]=5)=[C:36]5[NH:85][C:39](=[C:40]([C:46]6[CH:51]=[C:50]([O:52][CH2:53][CH2:54][CH2:55][CH2:56][CH2:57][CH2:58][CH2:59][CH2:60][CH2:61][CH3:62])[C:49]([O:63][CH2:64][CH2:65][CH2:66][CH2:67][CH2:68][CH2:69][CH2:70][CH2:71][CH2:72][CH3:73])=[C:48]([O:74][CH2:75][CH2:76][CH2:77][CH2:78][CH2:79][CH2:80][CH2:81][CH2:82][CH2:83][CH3:84])[CH:47]=6)[C:41]6[CH:42]=[CH:43][C:44]=2[N:45]=6)[CH:38]=[CH:37]5)[CH:33]=[CH:32]4)=[CH:27][CH:26]=3)=[CH:22][CH:23]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 136388361HCID 136388361, compound

Product 1

HCID 136388360HCID 136388360, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

5-[4-(12-Acetyloxy-dodecyloxy)-phenyl]-10,15,20-tris-(3,4,5-tridecyloxy-phenyl)-porphyrin (see Example 15) was heated to reflux in THF (10 ml) and ethanolic NaOH (excess) was added. When the reaction was complete as judged by thin layer chromatography, the solvent was evaporated under reduced pressure and the title compound was obtained by purification of the resultant residue by chromatography using a column of silica gel which was eluted with petroleum ether (b.p. 40-60° C.):THF (4:1 by volume).

Workup

  1. customthe solvent was evaporated under reduced pressure

Sources & evidence

ORD record
ord-8d141006ef7640fd9350c92838b712ef
Source dataset
uspto-grants-2003_10
Patent number
US06630128B1

Reaction notes

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