Thionyl Chloride → HCID 15294258, compound

HRID 987593Notes

Reaction equation

HRID 987593 reaction equation
[CH3:1][S:2]([C:5]1[CH:6]=[C:7]([CH:11]=[CH:12][C:13]=1[CH:14]([CH3:16])[CH3:15])[C:8](O)=[O:9])(=[O:4])=[O:3].S(Cl)([Cl:19])=O>CN(C=O)C.C1(C)C=CC=CC=1>[CH3:1][S:2]([C:5]1[CH:6]=[C:7]([CH:11]=[CH:12][C:13]=1[CH:14]([CH3:16])[CH3:15])[C:8]([Cl:19])=[O:9])(=[O:4])=[O:3]

Participants

5

Reactant 2

HCID 24386Thionyl ChlorideHCID 106339154-Isopropyl-3-methylsulfonylbenzoic acid

Product 1

HCID 15294258HCID 15294258, compound

Reagents, catalysts & solvents 2

HCID 6228DimethylformamideCatalystHCID 1140TolueneSolvent

Procedure

4.0 g of 3-methylsulfonyl-4-i-propylbenzoic acid, 1.5 ml of thionyl chloride and 3 drops of DMF are heated under reflux for 10 h in 30 ml of toluene. The solvent is subsequently removed in vacuo and the product is taken for further use without purification.

Workup

  1. customThe solvent is subsequently removed in vacuo
  2. customthe product is taken for further use without purification

Sources & evidence

ORD record
ord-eee581ab9e714f7f869a7ee3668cca98
Source dataset
uspto-grants-2003_10
Patent number
US06632840B1

Reaction notes

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