Tetrahydrofuran → 2-[5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-(1-cyclopropyl-2-hydroxyethyl)-3-methyl-2-oxopiperidin-3-yl]acetic acid
Reaction equation
[C:19]([Si:20]([c:21]1[cH:22][cH:23][cH:56][cH:57][cH:58]1)([O:24][CH2:25][CH:26]([CH:27]1[CH2:28][CH2:29]1)[N:30]1[C:31](=[O:55])[C:32]([CH3:50])([CH2:51][C:52](=[O:53])[OH:54])[CH2:33][CH:34]([c:43]2[cH:44][c:45]([Cl:49])[cH:46][cH:47][cH:48]2)[CH:35]1[c:36]1[cH:37][cH:38][c:39]([Cl:42])[cH:40][cH:41]1)[c:59]1[cH:60][cH:61][cH:62][cH:63][cH:64]1)([CH3:65])([CH3:66])[CH3:67].[CH2:68]1[O:69][CH2:70][CH2:71][CH2:72]1.[CH3:2][CH2:3][CH2:4][CH2:5][N+:6]([CH2:7][CH2:8][CH2:9][CH3:10])([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:15][CH2:16][CH2:17][CH3:18].[CH3:73][CH2:74][O:75][C:76](=[O:77])[CH3:78].[F-:1]>>[OH:24][CH2:25][CH:26]([CH:27]1[CH2:28][CH2:29]1)[N:30]1[C:31](=[O:55])[C:32]([CH3:50])([CH2:51][C:52](=[O:53])[OH:54])[CH2:33][CH:34]([c:43]2[cH:44][c:45]([Cl:49])[cH:46][cH:47][cH:48]2)[CH:35]1[c:36]1[cH:37][cH:38][c:39]([Cl:42])[cH:40][cH:41]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-019fbc19164e46d6928478bf8f46f91f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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