反应详情

A solution of 4-formyl-benzoic acid methyl ester (10 g), pyrrolidine (5.6 mL), and acetic acid (3.5 mL) in DCM (200 mL) was treated with sodium triacetoxyborohyride (20.65 g) and stirred at rt for 16 hours. The reaction mixture was then quenched with 3N NaOH (70 mL). The organic layer was dried over sodium sulfate and concentrated to yield the titled compound without purification.

1. customThe reaction mixture was then quenched with 3N NaOH (70 mL)
2. dry with materialThe organic layer was dried over sodium sulfate
3. concentrationconcentrated