Bromide ion → N-[2-(4-benzyloxy-3-methoxyphenyl)ethyl]-3-difluoromethoxy-2-(5,6,7,8-tetrahydronaphthalen-2-yl)acrylamide
Reaction equation
[Br-:42].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([O:33][CH3:34])[cH:11][c:12]([CH2:15][CH2:16][NH:17][C:18]([C:19](=[CH:20][OH:21])[c:22]2[cH:23][c:24]3[c:29]([cH:30][cH:31]2)[CH2:28][CH2:27][CH2:26][CH2:25]3)=[O:32])[cH:13][cH:14]1.[CH3:43][CH2:44][CH2:45][CH2:46][N+:47]([CH2:48][CH2:49][CH2:50][CH3:51])([CH2:52][CH2:53][CH2:54][CH3:55])[CH2:56][CH2:57][CH2:58][CH3:59].[CH3:60][O:61][CH2:62][CH2:63][O:64][CH3:65].[Cl:37][CH:38]([F:39])[F:40].[ClH:41].[K+:36].[OH-:35]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([O:33][CH3:34])[cH:11][c:12]([CH2:15][CH2:16][NH:17][C:18]([C:19](=[CH:20][O:21][CH:38]([F:39])[F:40])[c:22]2[cH:23][c:24]3[c:29]([cH:30][cH:31]2)[CH2:28][CH2:27][CH2:26][CH2:25]3)=[O:32])[cH:13][cH:14]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-1444d68cd8f44539956db0a9d99d3b42
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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