Hydroxide → 4-Chloro-7-hydroxy-9-(2,2,2-trifluoroethyl)-3,6,7,10-tetrahydropyrazolo[3,4-i][2]benzazepin-8-one
Reaction equation
[C:1](=[O:2])([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[O:9][CH:10]1[CH2:11][c:12]2[c:13]([c:14]3[cH:15][n:16][nH:17][c:18]3[c:19]([Cl:21])[cH:20]2)[CH2:22][N:23]([CH2:26][C:27]([F:28])([F:29])[F:30])[C:24]1=[O:25].[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[Li+:36].[OH-:37].[OH2:38]>>[OH:9][CH:10]1[CH2:11][c:12]2[c:13]([c:14]3[cH:15][n:16][nH:17][c:18]3[c:19]([Cl:21])[cH:20]2)[CH2:22][N:23]([CH2:26][C:27]([F:28])([F:29])[F:30])[C:24]1=[O:25]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-da0e50581e214a97997688ef36df1e78
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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