Tetrahydrofuran → methyl 4-(N-(2-(tert-butyldimethylsilyloxy)ethyl)-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamido)-3-chlorobenzoate
Reaction equation
[CH2:53]1[O:54][CH2:55][CH2:56][CH2:57]1.[CH3:23][Si:24]1([CH3:25])[C:26]([CH3:27])=[C:28]([CH3:29])[C:30]([CH3:31])=[N:32][SiH:33]1[CH3:34].[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[O:7][CH3:8])[cH:9][cH:10][c:11]1[NH:12][CH2:13][CH2:14][O:15][Si:16]([CH3:17])([CH3:18])[C:19]([CH3:20])([CH3:21])[CH3:22].[Na:35].[s:36]1[c:37]([C:50](=[O:51])[Cl:52])[cH:38][c:39]2[c:40]1-[c:41]1[c:42]([cH:46][cH:47][cH:48][cH:49]1)[O:43][CH2:44][CH2:45]2>>[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[O:7][CH3:8])[cH:9][cH:10][c:11]1[N:12]([CH2:13][CH2:14][O:15][Si:16]([CH3:17])([CH3:18])[C:19]([CH3:20])([CH3:21])[CH3:22])[C:50]([c:37]1[s:36][c:40]2[c:39]([cH:38]1)[CH2:45][CH2:44][O:43][c:42]1[c:41]-2[cH:49][cH:48][cH:47][cH:46]1)=[O:51]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-0ec0080dac354bda8176623d04ce3f48
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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