Hydrogen Bromide → 3-(4-fluorophenyl)-1-{2-oxo-2-[5-(trifluoromethyl)-1,3-dihydro-2H-isoindol-2-yl]ethyl}pyrrolidin-2-one
Reaction equation
[BrH:18].[CH2:32]([N:33]=[C:34]=[N:35][CH2:36][CH2:37][CH2:38][N:39]([CH3:40])[CH3:41])[CH3:42].[Cl:43][CH2:44][Cl:45].[F:19][C:20]([c:21]1[cH:22][c:23]2[c:27]([cH:28][cH:29]1)[CH2:26][NH:25][CH2:24]2)([F:30])[F:31].[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[C:9](=[O:17])[N:10]([CH2:13][C:14](=[O:15])[OH:16])[CH2:11][CH2:12]2)[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[C:9](=[O:17])[N:10]([CH2:13][C:14](=[O:16])[N:25]3[CH2:24][c:23]4[cH:22][c:21]([C:20]([F:19])([F:30])[F:31])[cH:29][cH:28][c:27]4[CH2:26]3)[CH2:11][CH2:12]2)[cH:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-1a14bacd5b3a493e854d61204b028327
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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