Acetate → tert-butyl 1-(4-(1-oxo-3-phenyl-1H-inden-2-yl)phenyl)cyclobutylcarbamate

HRID 99839Notes

Reaction equation

HRID 99839 reaction equation
[Br:1][c:2]1[c:3]([CH:4]=[O:5])[cH:6][cH:7][cH:8][cH:9]1.[C:65]([O-:66])(=[O:67])[CH3:68].[C:70]([O-:71])(=[O:72])[CH3:73].[CH2:43]([N+:44]([CH2:45][CH2:46][CH2:47][CH3:48])([CH2:49][CH2:50][CH2:51][CH3:52])[CH2:53][CH2:54][CH2:55][CH3:56])[CH2:57][CH2:58][CH3:59].[CH3:37][C:38](=[O:39])[O-:40].[Cl-:42].[Na+:36].[O:60]=[CH:61][N:62]([CH3:63])[CH3:64].[OH2:41].[Pd+2:69].[c:10]1([C:16]#[C:17][c:18]2[cH:19][cH:20][c:21]([C:24]3([NH:28][C:29]([O:30][C:31]([CH3:32])([CH3:33])[CH3:34])=[O:35])[CH2:25][CH2:26][CH2:27]3)[cH:22][cH:23]2)[cH:11][cH:12][cH:13][cH:14][cH:15]1>>[c:2]12[c:3]([cH:6][cH:7][cH:8][cH:9]1)[C:4](=[O:5])[C:17]([c:18]1[cH:19][cH:20][c:21]([C:24]3([NH:28][C:29]([O:30][C:31]([CH3:32])([CH3:33])[CH3:34])=[O:35])[CH2:25][CH2:26][CH2:27]3)[cH:22][cH:23]1)=[C:16]2[c:10]1[cH:11][cH:12][cH:13][cH:14][cH:15]1

Participants

10

Reactant 9

HCID 175Acetate3×HCID 312ChlorideHCID 923Sodium ionHCID 962WaterHCID 6228DimethylformamideHCID 16028TetrabutylammoniumHCID 811292-BromobenzaldehydeHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 57805483HCID 57805483, compound

Product 1

HCID 67067872tert-butyl 1-(4-(1-oxo-3-phenyl-1H-inden-2-yl)phenyl)cyclobutylcarbamate

Sources & evidence

ORD record
ord-cdb2e7a5325f4a35ac9db02b29d7f61b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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