2-Methoxyethylamine → 6-[3-(4-Fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-N-(2-methoxy-ethyl)-nicotinamide
Reaction equation
[CH3:10][O:11][C:12]([c:13]1[cH:14][n:15][c:16]([O:19][CH2:20][c:21]2[c:22](-[c:28]3[cH:29][cH:30][c:31]([F:34])[cH:32][cH:33]3)[n:23][o:24][c:25]2[CH2:26][OH:27])[cH:17][cH:18]1)=[O:35].[CH3:1][Al:2]([CH3:3])[CH3:4].[CH3:5][O:6][CH2:7][CH2:8][NH2:9].[O:36]1[CH2:37][CH2:38][O:39][CH2:40][CH2:41]1>>[CH3:5][O:6][CH2:7][CH2:8][NH:9][C:12](=[O:11])[c:13]1[cH:14][n:15][c:16]([O:19][CH2:20][c:21]2[c:22](-[c:28]3[cH:29][cH:30][c:31]([F:34])[cH:32][cH:33]3)[n:23][o:24][c:25]2[CH2:26][OH:27])[cH:17][cH:18]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-bc5e6c16bb77465aa8bac4b61ad9133a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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