6-Methylpyridin-3-ol

2-Methyl-5-hydroxypyridine

HCID 14275CAS 1121-78-4

Grundinformationen

Standard-SMILES
Cc1ccc(O)cn1
InChIKey
DHLUJPLHLZJUBW-UHFFFAOYSA-N
Summenformel
C6H7NO
Durchschnittliche Molmasse
109,13 g/mol
Monoisotopische Masse
109,05276385

Namen und Bezeichner

Bevorzugter Name
2-Methyl-5-hydroxypyridine
IUPAC
6-methylpyridin-3-ol
Lokaler Name
6-Methylpyridin-3-ol
Englischer Name
3-Hydroxy-6-methylpyridine
Summenformel
C6H7NO
Molmasse
109.13

Namen und Synonyme

5-Hydroxy-2-methylpyridine1121-78-46-Methylpyridin-3-ol2-Methyl-5-hydroxypyridine3-HYDROXY-6-METHYLPYRIDINE6-Methyl-3-pyridinol3-Pyridinol, 6-methyl-6-Methyl-3-hydroxypyridine5-Hydroxy-2-picoline2-methyl-5-pyridinolDTXSID4051580UKE16JP1JR
Weitere Namen anzeigen
6-methyl-3-pyridinoTIMTEC-BB SBB0043492-Methylpyridin-5-ol6-Methyl-3-pyridineol3-HYDOXY-6-METHYLPYRIDINE
EINECS 214-337-8NSC 27963BRN 0107077NSC-279633-PYRIDOL, 6-METHYL-DTXCID8030132DHLUJPLHLZJUBW-UHFFFAOYSA-5-21-02-00139 (Beilstein Handbook Reference)

Datenbank-Bezeichner

CAS
1121-78-4
PubChem CID
14275
DTXSID
DTXSID4051580
ChEMBL
CHEMBL134979
UNII
UKE16JP1JR
EC Number
214-337-8
Nikkaji
J121J

Eigenschaften

Berechnete Struktureigenschaften

XLogP
0,8
Polarare Oberfläche (TPSA)
33,1 Ų
H-Brücken-Donoren
1
H-Brücken-Akzeptoren
2
Frei drehbare Bindungen
0
Schwere Atome
8

Experimentelle und physikochemische Eigenschaften

Kovats Retention Index2430
Collision Cross Section · 1 Eintrag

119.4 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID4051580];118.1 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: APCI+; Dataset: TOXCAST; Source Identifier: DTXSID4051580];120.4 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID4051580]

Physikochemische Eigenschaften

Schmelzpunkt
168 · 168-170 °C(lit.)
Siedepunkt
204.59 °C · 204.59°C (rough estimate)
Dichte
1.1143 · 1.1143 (rough estimate)
Brechungsindex
1.504 · 1.5040 (estimate)
storage temp.
2 · under inert gas (nitrogen or Argon) at 2-8°C
Löslichkeit
dichloromethane: soluble

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

Danger

H302 (88.9%): Harmful if swallowed [Warning Acute toxicity, oral];H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation];H318 (88.9%): Causes serious eye damage [Danger Serious eye damage/eye irritation];H319 (11.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (97.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 45 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Hazard Classes and CategoriesAcute Tox. 4 (88.9%);Skin Irrit. 2 (100%);Eye Dam. 1 (88.9%);Eye Irrit. 2 (11.1%);STOT SE 3 (97.8%)

Sicherheitsdaten

wgk
3
hs_code
29333990
RTECS-Nr.
UU7714900
risk_code
22-37/38-41-40-36/37/38
Toxizität
mouse,LD50,intraperitoneal,846mg/kg (846mg/kg),Toxicon. Vol. 23, Pg. 815, 1985.
hazard_code
Xn,Xi

Chemie und Industrie

Anwendungen · 1 Eintrag

Verwenden5-Hydroxy-2-methylpyridine was used as starting reagent for the synthesis of 5-[(4-methoxybenzyl)oxy]-2-pyridinecarbaldehyde. It was used in synthesis of [HNC6H6OH]2[Cu(NC5H5)4(NbOF5)2].It was used as ligand of a platinum complex which showed protein kinase inhibitory action at nanomolar levels. It forms a chiral pyridinium ionic liquid on reaction with L-menthol chloromethyl ether.

Anbieter50 Anbieter

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海泰矶林实业有限公司02150630626 17717886015 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
韶远科技(上海)有限公司021-50795510 4000665055 · [email protected]
常州思丹德化工有限公司0519-85607885 13776800733 · [email protected]

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