Hexafluoropropylene oxide (HCID 9883)

Überblick

Hexafluoropropylene oxide is a colorless odorless gas. It is shipped as a liquefied gas under its vapor pressure. Contact with the liquid can cause frostbite. Its vapors are heavier than air. It can cause asphyxiation by the displacement of air. Exposure of the container to prolonged heat or fire may cause it to rupture violently and rocket.

Namen und Bezeichner

Bevorzugter Name: Hexafluoropropylene oxide
IUPAC: 2,2,3-trifluoro-3-(trifluoromethyl)oxirane
Lokaler Name: Trifluor(trifluormethyl)oxiran
Englischer Name: Hexafluoropropylene oxide
Summenformel: C3F6O
Molmasse: 166.02

Namen und Synonyme

Hexafluoropropylene oxide428-59-1Hexafluoropropene oxide2,2,3-Trifluoro-3-(trifluoromethyl)oxiraneHfpoTRIFLUORO(TRIFLUOROMETHYL)OXIRANEPerfluoropropylene oxideHexafluoro-1,2-epoxypropaneHexafluoropropene epoxideHexafluoropropylene epoxideHexafluoroepoxypropanePropylene oxide hexafluoride

Weitere Namen anzeigen

1,1,2,3,3,3-Hexafluoro-1,2-epoxypropaneC3F6ONA 1956(S) TRIMETHYLOXIRANE

Oxirane, trifluoro(trifluoromethyl)-JPY12AP87NPropane, 1,2-epoxy-1,1,2,3,3,3-hexafluoro-RefChem:146014ACETONE, HEXAFLUOROHFPO hexafluoropropylene oxide207-050-4Poly(perfluoropropyleneoxide)

Datenbank-Bezeichner

CAS: 428-59-1
PubChem CID: 9883
DTXSID: DTXSID6029177
UNII: JPY12AP87N
EC Number: 207-050-4
Nikkaji: J27.198E

Eigenschaften

Berechnete Struktureigenschaften

XLogP: 2,1
Polarare Oberfläche (TPSA): 12,5 Å²
H-Brücken-Donoren: 0
H-Brücken-Akzeptoren: 7
Frei drehbare Bindungen: 0
Schwere Atome: 10
Formalladung: 0
Komplexität: 161

Experimentelle und physikochemische Eigenschaften

PFAS · 6 Einträge

PFAS -> OECD Category

PFAS -> Suspected persistent, mobile, toxic (PMT) PFAS or PFAS-like compounds

PFAS

PFAS -> Intentionally added food contact chemicals

PFAS -> PFAS identified in REACH Regulation EC No. 1272/2008

PFAS -> Other/unspecified

PolymersPlastics & Rubber -> Other Monomers

Boiling Point-18 °F at 760 mmHg (NTP, 1992)

Decomposition · 1 Eintrag

AT TEMP BETWEEN 500-800 °C, CARBONYL FLUORIDE (COF2) IS DOMINANT PYROLYSIS PRODUCT. THIS GAS IS VERY SUSCEPTIBLE TO HYDROLYSIS, READILY YIELDING HYDROFLUORIC ACID & CARBON DIOXIDE. ABOVE 800 °C, THE PYROLYSIS PRODUCTS CONSIST OF INORGANIC FLUORIDE, A LITTLE TETRAFLUOROMETHANE & CARBON DIOXIDE. /POLYFLUORINES/

Melting Point-200 °F (NTP, 1992)

Physical Description · 3 Einträge

Hexafluoropropylene oxide is a colorless odorless gas. It is shipped as a liquefied gas under its vapor pressure. Contact with the liquid can cause frostbite. Its vapors are heavier than air. It can cause asphyxiation by the displacement of air. Exposure of the container to prolonged heat or fire may cause it to rupture violently and rocket.

Gas Vapor; CBI; Liquid

Colorless odorless gas; Shipped liquefied under its vapor pressure; [CAMEO]

Physikochemische Eigenschaften

Schmelzpunkt: -129 °C · -129°C
Siedepunkt: 42 °C · −42 °C(lit.)
Dichte: 1.67 · 1.67±0.1 g/cm3(Predicted)
Dampfdruck: 680.85 kPa · 680.85kPa at 25℃
Wasserlöslichkeit: 16.3 μg/L · 16.3μg/L at 22.7℃
Henry's Law Constant: 9.3 · 9.3×10-6 mol/(m3Pa) at 25℃, Clever et al. (2005)
InChI: InChI=1S/C3F6O/c4-1(2(5,6)7)3(8,9)10-1
InChIKey: PGFXOWRDDHCDTE-UHFFFAOYSA-N
SMILES: O1C(F)(C(F)(F)F)C1(F)F
LogP: 1.72 at · 1.72 at 25℃
CAS Datenbank: 428 · 428-59-1(CAS DataBase Reference)
NIST chemische Informationen: Oxirane, trifluoro(trifluoromethyl)-(428-59-1)
EPA chemische Informationen: 2 · Oxirane, 2,2,3-trifluoro-3-(trifluoromethyl)- (428-59-1)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 24.2% (16 of 66) of reports.

Danger

H280 (74.2%): Contains gas under pressure; may explode if heated [Warning Gases under pressure]

P260, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P316, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, P410+P403, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 66 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

Gefahrenhinweise

Regulatory Information · 4 Einträge

Oxirane, 2,2,3-trifluoro-3-(trifluoromethyl)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Oxirane, 2,2,3-trifluoro-3-(trifluoromethyl)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

S - indicates a substance that is identified in a final Significant New Use Rule.

Status: Active Update: 21-01-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/5721

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

DOT LabelNon-Flammable Gas

Fire HazardsExcerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:

Health HazardsExcerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:

Hazards Summary · 1 Eintrag

May polymerize; Containers may explode from prolonged heat; Evaporating liquid can cause frostbite; In confined space spill, may displace air and act as simple asphyxiant; [CAMEO] May explode if heated under confinement; An irritant; In confined space spill, may displace air and act as simple asphyxiant; [MSDSonline]

Reactive GroupEpoxides

Sicherheit und Schutzausrüstung

Fire FightingExcerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:

First Aid · 1 Eintrag

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill ResponseExcerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:

Preventive Measures · 1 Eintrag

VENTILATION CONTROL: ...WHERE...RESINS ARE LIKELY TO UNDERGO PYROLYSIS & DECOMP DURING PROCESSING, PROVISION SHOULD BE MADE FOR ADEQUATE LOCAL EXHAUST & GENERAL VENTILATION TO KEEP CONCN OF DECOMP PRODUCTS AS LOW AS POSSIBLE. /POLYFLUORINES/

Isolation and EvacuationExcerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:

Personal Protective Equipment (PPE)Excerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:

Toxikologische Informationen

Adverse EffectsOther Poison - Simple Asphyxiant

Human Toxicity Excerpts · 1 Eintrag

A UNIQUE EFFECT FROM PYROLYSIS PRODUCTS OF PTFE /POLYTETRAFLUOROETHYLENE/ RESINS...BEEN OBSERVED IN MAN... THIS IS AN INFLUENZA-LIKE SYNDROME RESEMBLING METAL FUME FEVER & HAS BEEN TERMED "POLYMER FUME FEVER". IT IS SELF-LIMITING, LASTS...24-48 HR & REQUIRES ONLY SYMPTOMATIC TREATMENT. /POLYFLUORINES/

Non-Human Toxicity Excerpts · 1 Eintrag

IN ACUTE STUDIES WITH MICE & RATS IT CAUSED CHANGES IN LIVER & KIDNEY. IN SPLEEN IT CAUSED VASCULAR PERMEABILITY & DEGENERATIVE DYSTROPHIC CHANGES & INFLAMMATION. EXTENT & NATURE OF TOXICITY DEPENDS UPON TYPE OF METABOLITES THAT ARE PRODUCED.

Probable Routes of Human Exposure · 1 Eintrag

A UNIQUE EFFECT FROM PYROLYSIS PRODUCTS OF PTFE /POLYTETRAFLUOROETHYLENE/ RESINS...BEEN OBSERVED IN MAN... THIS IS AN INFLUENZA-LIKE SYNDROME RESEMBLING METAL FUME FEVER & HAS BEEN TERMED "POLYMER FUME FEVER". IT IS SELF-LIMITING, LASTS...24-48 HR & REQUIRES ONLY SYMPTOMATIC TREATMENT. /POLYFLUORINES/

Sicherheitsdaten

wgk: 3
tsca: TSCA listed
ridadr: UN 1956 2.2
risk_code: 36/37/38-44
hazard_code: Xi
hazard_note: Irritant
safety_code: 7-26-37/39-38
hazard_class: 2.2
Giftige Stoffe Daten: 428-59-1(Hazardous Substances Data)

Chemie und Industrie

Verwendung und Herstellung

Uses · 2 Einträge

Used as monomer for heat-resistant hexafluoropropylene oxide polymers; [HSDB]

MONOMER FOR HEXAFLUOROPROPYLENE OXIDE POLYMERS THAT ARE HEAT RESISTANT TO 410 °C

U.S. Production2023: 2,500,000 - <4,000,000 lb

Industry UsesIntermediate

Methods of ManufacturingOXIDATION OF HEXAFLUOROPROPYLENE WITH ALKALINE HYDROGEN PEROXIDE...ABOUT -30 °C.

Use ClassificationPFAS (per- and polyfluoroalkyl substances) -> OECD Category

General Manufacturing Information · 4 Einträge

All Other Basic Organic Chemical Manufacturing

Oxirane, 2,2,3-trifluoro-3-(trifluoromethyl)-: ACTIVE

"FREON E" /IS/ TRADEMARK FOR SERIES OF HYDROGEN END-CAPPED TETRAFLUOROETHYLENE EPOXIDE POLYMERS HAVING A DP /DEGREE OF POLYMERIZATION/ UP TO 10. BOILING RANGE 39-490 °C. HIGH DIELECTRIC CONSTANT. USED AS COOLANTS IN ELECTRONIC DEVICES. /FREON E/

"KRYTOX" /IS/ TRADEMARK FOR A SERIES OF HEXAFLUOROPROPYLENE EPOXIDE POLYMERS OF MEDIUM MOLECULAR WT, USED AS LUBRICATING OILS & GREASES. FOR USE IN HIGH TEMP OR CORROSIVE CONDITIONS; GOOD CHEM INERTNESS, EVEN WITH BOILING SULFURIC ACID; LOW SOLUBILITY IN MOST SOLVENTS; GOOD LUBRICITY UNDER LOAD... /KRYTOX/

Anwendungen · 1 Eintrag

VerwendenHexafluoropropylene oxide is an important intermediate of organic fluorine material.HFPO is mainly used in the manufacture of high-quality fluorinated compounds.It is the main component of perfluor-vinyl ether(PPVE,PSVE,PFVE,PMVE) and the monomer of fluorinated surfactants and fluorinated ether oil.